RÉSUMÉ: Cet article propose une analyse «habermasienne» du fait de dire des conneries qui diffère de l’approche bien connue de Harry Frankfurt. Il y est question de démontrer que la théorie de l’agir communicationnel d’Habermas fournit de meilleurs outils conceptuels pour une telle analyse. Il sera également démontré que les partisans d’Habermas devraient être préoccupés par ce phénomène. Déconner perturbe la transition au discours; elle interrompt la force liante de l’agir communicationnel (qui est à la base de l’explication d’Habermas sur (...) l’intégration sociale) et, suffisamment répandu pour en altérer les attitudes fondamentales à l’égard du discours public, le déconnage met en question le statut de la théorie de l’agir communicationnel d’Habermas comme une reconstruction de la connaissance intuitive des locuteurs compétents. (shrink)

What motivates grandparents to their altruism? We review answers from evolutionary theory, sociology, and economics. Sometimes in direct conflict with each other, these accounts of grandparental investment exist side-by-side, with little or no theoretical integration. They all account for some of the data, and none account for all of it. We call for a more comprehensive theoretical framework of grandparental investment that addresses its proximate and ultimate causes, and its variability due to lineage, values, norms, institutions (e.g., inheritance laws), and (...) social welfare regimes. This framework needs to take into account that the demographic shift to low fecundity and mortality in economically developed countries has profoundly altered basic parameters of grandparental investment. We then turn to the possible impact of grandparental acts of altruism, and examine whether benefits of grandparental care in industrialized societies may manifest in terms of less tangible dimensions, such as the grandchildren's cognitive and verbal ability, mental health, and well-being. Although grandparents in industrialized societies continue to invest substantial amounts of time and money in their grandchildren, we find a paucity of studies investigating the influence that this investment has on grandchildren in low-risk family contexts. Under circumstances of duress there is converging evidence that grandparents can provide support that helps to safeguard their children and grandchildren against adverse risks. We conclude by discussing the role that grandparents could play in what has been referred to as Europe's demographic suicide. (shrink)

Bisphosphonates are a class of drugs which have shown good efficacy in the treatment of post‐menopausal osteoporosis, as well as a good safety profile. However, side‐effects such as risk for atypical femoral fractures (AFF) have appeared, leading to a decline in use of the drugs by many patients who would benefit from the treatment. While patient characteristics have contributed to improved understanding of risk factors, the mechanisms involved that explain AFF risk have not appeared. Recently, the possibility that the mechanism(s) (...) involved drug‐induced modification of cells of the nutrient canals of the femur and subsequent compromise in the bone matrix has been published. The present Hypothesis article builds on the concept presented earlier and expands into biomechanical considerations. An analogy of the mechanisms involved to a real‐life scenario is also presented. While this analogy has limitations, consideration of the biomechanical implications of progressive alterations to defects presented by compromised nutrient canal‐bone matrix also presents potential relationships with AFF risk. (shrink)

This series of three articles describes the history of land law shared by the British and American legal systems, and how and why these legal traditions have diverged from each other in modern times. This Article - part 1 in this series - describes the emerging customs and laws regarding land rights among early inhabitants of Britain, and how succeeding invasions and occupation by Celtic, Roman, Germanic, and Norman peoples altered these customs and laws. The Article details the profound changes (...) in land law worked by massive economic changes in early British society, including sociological occurrences such as the Black Death, and the adoption of laws, such as the Statute of Uses in 1536. (shrink)

Art restoration has been around as long as human beings have been involved with artifacts and works of art. Pliny mentions the Shrine of Ceres in the Circus Maximus at Rome.1 When the shrine was undergoing restoration, the embossed work of the walls was cut out and enclosed in framed panels, and figures were taken from the pediment and dispersed. Alteration, or the lack of it, clearly impacts the aesthetic appreciation of works of art, and the hermeneutics of that debate (...) are important in terms of both education and historical understanding.The purpose of this article is to survey the field of restoration and its interaction with problems of interpretation, aesthetic debate... (shrink)

Miller's formulation of problems was controlled by tensions between conscious" and "mechanical" and between "understanding" and "mystery." The mechanical world, devoid of morality and purpose, was incompatible with conscious beauty and ethics; within the "conscious" the optimistic drive for knowledge about an intelligible universe conflicted with belief in an unknowable, awful universe. Miller's history was also informed by his sense of development: history proceeds in a continuing series of interactions between inherited cultural forms, and immediate environmental circumstances. Culture is never (...) merely the "product" of environment, but an active agent in the interaction. The search for "historical knowledge" itself proceeds on the terms of this interaction. Here Miller rejected both positivism and the capricious relativism of Becker for the harder relativism subsequently articulated by Kuhn and Toulmin: "forms" are neither wholly arbitrary nor entirely discovered in "the facts," but are instead the inheritance and creation of the historian, altered and confirmed by his experience. (shrink)

Concerns about business ethics have led many business schools to integrate ethics into the curriculum, with mixed results (May, Luth, & Schwoerer 2014, Wang & Calvano 2015, Waples, Antes, Murphy, Connelly & Mumford 2009). This paper seeks to improve our understanding of business students’ ethics by looking into their identity, a cognitive lens by which students see themselves and interpret their environment (Triandis 1989) and that can be relatively malleable to priming and socializing processes (Vignoles, Schwartz, & Luyckx 2011, Ybarra (...) & Trafimow 1998). Results show that undergraduate students with higher individual and lower collective identities report lower intentions to behave ethically. Moreover, our results show that a business education has the power to influence students’ ethical intentions by altering their individual and collective identities. Our results suggest that business schools should consider the effects of their curriculum and pedagogies on the development of individual and collective identities to educate more ethical business students. (shrink)

Coordinated daily rhythms are evident in most aspects of our physiology, driven by internal timing systems known as circadian clocks. Our understanding of how biological clocks are built and function has grown exponentially over the past 20 years. With this has come an appreciation that disruption of the clock contributes to the pathophysiology of numerous diseases, from metabolic disease to neurological disorders to cancer. However, it remains to be determined whether it is the disruption of our rhythmic physiology per se (...) (loss of timing itself), or altered functioning of individual clock components that drive pathology. Here, we review the importance of circadian rhythms in terms of how we (and other organisms) relate to the external environment, but also in relation to how internal physiological processes are coordinated and synchronized. These issues are of increasing importance as many aspects of modern life put us in conflict with our internal clockwork. (shrink)

Next SectionObjectives To evaluate the adequacy of paediatric informed consent and its augmentation by a supplemental computer-based module in paediatric endoscopy. Methods The Consent-20 instrument was developed and piloted on 47 subjects. Subsequently, parents of 101 children undergoing first-time, diagnostic upper endoscopy performed under moderate IV sedation were prospectively and consecutively, blinded, randomised and enrolled into two groups that received either standard form-based informed consent or standard form-based informed consent plus a commercial (Emmi Solutions, Inc, Chicago, Il), sixth grade level, (...) interactive learning module (electronic assisted consent). Anonymously and electronically, the subjects' anxiety (State Trait Anxiety Inventory), satisfaction (Modified Group Health Association of America), number of questions asked, and attainment of informed consent were assessed (Consent-20). Statistics were calculated using t test, paired t test, and Mann Whitney tests. Results The ability to achieve informed consent, as measured by the new instrument, was 10% in the control form-based consent group and 33% in the electronic assisted consent group (p<0.0001). Electronically assisting form-based informed consent did not alter secondary outcome measures of subject satisfaction, anxiety or number of questions asked in a paediatric endoscopy unit. Conclusions This study demonstrates the limitations of form-based informed consent methods for paediatric endoscopy. It also shows that even when necessary information was repeated electronically in a comprehensive and standardised video, informed consent as measured by our instrument was incompletely achieved. The supplemental information did, however, significantly improve understanding in a manner that did not negatively impact workflow, subject anxiety or subject satisfaction. Additional study of informed consent is required. Clinical trial registration number ClinicalTrials.gov Identifier NCT00899392. (shrink)

Protection against bacterial and viral pathogens by antibodies has always been thought to end at the cell surface. Once inside the cell, a pathogen was understood to be safe from humoral immunity. However, it has now been found that antibodies can routinely enter cells attached to viral particles and mediate an intracellular immune response. Antibody‐coated virions are detected inside the cell by means of an intracellular antibody receptor, TRIM21, which directs their degradation by recruitment of the ubiquitin‐proteasome system. In this (...) article we assess how this discovery alters our view of the way in which antibodies neutralise viral infection. We also consider the antiviral function of TRIM21 in the context of its other reported roles in immune signalling and autoimmunity. Finally, we discuss the conceptual implications of intracellular antibody immunity and how it alters our view of the discrete separation of extracellular and intracellular environments. (shrink)

Background: The proprioceptive neuromuscular facilitation reciprocal contraction pattern has the potential to increase the maximum rate of torque development. However, it is a more complex resistive exercise task and may interfere with improvements in the maximum rate of torque development due to motor skill learning, as observed for unidirectional contractions. The purpose of this study was to examine the cost-benefit of using the PNF exercise technique to increase the maximum rate of torque development.Methods: Twenty-six participants completed isometric maximal extension-to-flexion or (...) flexion-only contractions at the wrist. Ten of the assigned contractions were performed on each of three sessions separated by 48-h for skill acquisition. Retention was assessed with 5 contractions performed 2-weeks after acquisition. Torque and surface electromyographic activity were analyzed for evidence of facilitated contractions between groups, as well as alterations in muscle coordination assessed across test sessions. The criterion measures were: mean maximal isometric wrist flexion toque; the maximal rate of torque development ; root-mean-square error variability of the rate of torque versus torque phase-plane; the rate of wrist flexion muscle activation ; a coactivation ratio for wrist flexor and extensor sEMG activity; and wrist flexor electromechanical delay.Results: There were no significant differences between groups with respect to maximal wrist flexion torque, dτ/dtmax or RMSE variability of torque trajectories. Both groups exhibited a progressive increase in maximal strength and in dτ/dtmax from the start of acquisition to retention. RMSE was lowest after a 2-week rest interval. There were no significant differences between groups in the rate of muscle activation or the coactivation ratio. There was a reduction in coactivation that was retained after a 2-week rest interval. Alternatively, EMD was significantly greater in the experimental group across all sessions. However, both groups had a similar pattern of improvement to the third consecutive day of testing, but returned close to baseline value after the 2-week rest interval.Discussion: The wrist extension-to-flexion contraction pattern did not result in a greater maximal rate of torque development than simple contractions of the wrist flexors. There was no difference between groups with respect to motor skill learning. The main adaptation in neuromotor control was a decrease in coactivation, not the maximal rate of muscle activation. (shrink)

Two experiments using a realistic version of the selection task examined the relationship between participants' probability estimates of finding a counter example and their selections. Experiment 1 used everyday categories in the context of a scenario to determine whether or not the number of instances in a category affected the estimated probability of a counter-example. Experiment 2 modified the scenario in order to alter participants' estimates of finding a specific counter-example. Unlike Kirby 1994a, but consistent with his proposals, both (...) studies showed that probability estimates significantly predicted selection. Overall results point to the value of understanding selections in terms of their subjective expected utility. (shrink)

Failure of substitutivity of coreferential terms, one of the hallmarks of referential opacity, is standardly explained in terms of the presence of an expression (such as a verb of propositional attitude, a modal adverb or quotation marks) with opacity-inducing properties. It is thus assumed that any term in a complex expression for which substitutivity fails will be within the scope of an expression of one of these types, and that where there is an expression of one of these types there (...) will be failure of substitutivity for terms within its scope. I shall discuss a series of examples that have been thought to challenge this explanation by exhibiting failure of substitutivity of coreferential terms for positions not within the scope of any of the standard opacity-inducing expressions. If these examples are genuine, then the usual explanations of opacity are either incomplete – because there are sources of opacity other than those standardly identified, or completely mistaken – because the standardly identified expressions are not causes of opacity. I will argue, however, that the examples only exhibit failure of substitutivity of non-coreferential terms, and, hence, do not present a challenge to standard explanations of opacity. (shrink)

Pancreatitis is a complex, progressively destructive inflammatory disorder. Alcohol was long thought to be the primary causative agent, but genetic contributions have been of interest since the discovery that rare PRSS1, CFTR and SPINK1 variants were associated with pancreatitis risk. We now report two associations at genome-wide significance identified and replicated at PRSS1-PRSS2 and X-linked CLDN2 through a two-stage genome-wide study. The PRSS1 variant likely affects disease susceptibility by altering expression of the primary trypsinogen gene. The CLDN2 risk allele is (...) associated with atypical localization of claudin-2 in pancreatic acinar cells. The homozygous CLDN2 genotype confers the greatest risk, and its alleles interact with alcohol consumption to amplify risk. These results could partially explain the high frequency of alcohol-related pancreatitis in men. © 2012 Nature America, Inc. All rights reserved. (shrink)

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain (...) in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

Russellian monism offers a distinctive perspective on the relationship between the physical and the phenomenal. For example, on one version of the view, phenomenal properties are the categorical bases of fundamental physical properties, such as mass and charge, which are dispositional. Russellian monism has prominent supporters, such as Bertrand Russell, Grover Maxwell, Michael Lockwood, and David Chalmers. But its strengths and shortcomings are often misunderstood. In this paper we try to eliminate confusions about the view and defend it from (...) criticisms. We present its core and distinguish different versions of it. We then compare these versions with traditional theories, such as physicalism, dualism, and idealism. We also argue that the knowledge argument and the conceivability argument are consistent with Russellian monism and that existing arguments against the view, such as the argument from weirdness, are not decisive. We conclude that Russellian monism is an attractive view that deserves serious consideration. (shrink)

BackgroundThe increased risk of developing attention-deficit hyperactivity disorder (ADHD) in extremely preterm infants is well-documented. Better understanding of perinatal risk factors, particularly those that are modifiable, can inform prevention efforts.MethodsWe examined data from the Extremely Low Gestational Age Newborns (ELGAN) Study. Participants were screened for ADHD at age 10 with the Child Symptom Inventory-4 (N = 734) and assessed at age 15 with a structured diagnostic interview (MINI-KID) to evaluate for the diagnosis of ADHD (N = 575). We studied associations (...) of pre-pregnancy maternal body mass index (BMI), pregestational and/or gestational diabetes, maternal smoking during pregnancy (MSDP), and hypertensive disorders of pregnancy (HDP) with 10-year and 15-year ADHD outcomes. Relative risks were calculated using Poisson regression models with robust error variance, adjusted for maternal age, maternal educational status, use of food stamps, public insurance status, marital status at birth, and family history of ADHD. We defined ADHD as a positive screen on the CSI-4 at age 10 and/or meeting DSM-5 criteria at age 15 on the MINI-KID. We evaluated the robustness of the associations to broadening or restricting the definition of ADHD. We limited the analysis to individuals with IQ ≥ 70 to decrease confounding by cognitive functioning. We evaluated interactions between maternal BMI and diabetes status. We assessed for mediation of risk increase by alterations in inflammatory or neurotrophic protein levels in the first week of life.ResultsElevated maternal BMI and maternal diabetes were each associated with a 55–65% increase in risk of ADHD, with evidence of both additive and multiplicative interactions between the two exposures. MSDP and HDP were not associated with the risk of ADHD outcomes. There was some evidence for association of ADHD outcomes with high levels of inflammatory proteins or moderate levels of neurotrophic proteins, but there was no evidence that these mediated the risk associated with maternal BMI or diabetes.ConclusionContrary to previous population-based studies, MSDP and HDP did not predict ADHD outcomes in this extremely preterm cohort, but elevated maternal pre-pregnancy BMI, maternal diabetes, and perinatal inflammatory markers were associated with increased risk of ADHD at age 10 and/or 15, with positive interaction between pre-pregnancy BMI and maternal diabetes. (shrink)

The June 1975 issue of the Hastings Center Report published the Deliberations and Recommendations of the National Commission for the Protection of Human Subjects concerning the regulation of fetal experimentation. The Commission's most controversial conclusions were as follows: First, it voted to allow non‐therapeutic research on the human fetus, provided important biomedical knowledge could not be gained in any other way, proper consent had been obtained, and the research imposed “minimal or no risk to the well‐being of the fetus” (Recommendation (...) 4). Because interpretations of the last phrase varied in the case of fetuses scheduled for abortion, the Commission recommended that a national ethical review body be able to rule on disputed cases (Recommendation 5). In the case of research during abortion and research on the non‐viable fetus ex utero, the Commission's interpretation of permissible “harm” was restricted to the proviso that “no intrusion into the fetus [may be] made which alters the duration of life” (Recommendation 6). The Commission also recommended further research on abortion techniques (Recommendation 12). The Secretary of Health, Education and Welfare accepted the Commission's Recommendations almost without change—the major modification was to request paternal consent rather than to rely on the fact that “the father has not objected.” The DHEW regulations were published in the Federal Register on Friday, August 8, 1975, and written comments on them were invited. Already, however, a number of commentators including several members of the Commission had offered either dissenting or qualifying remarks. Some are printed here. (shrink)

Vision, more than any other sense, dominates our mental life. Our visual experience is just so rich, so detailed, that we can hardly distinguish that experience from the world itself. Even when we just think about the world and don't look at it directly, we can't help but 'imagine' what it looks like. We think of 'seeing' as being a conscious activity--we direct our eyes, we choose what we look at, we register what we are seeing. The series of events (...) described in this book radically altered this attitude towards vision. This book describes one of the most extraordinary neurological cases of recent years--one that profoundly changed scientific views on consciousness. It is the story of Dee Fletcher--a woman recently blinded--who became the subject of a series of scientific studies. As events unfolded, Milner and Goodale found that Dee wasn't in fact blind--she just didn't know that she could see. Taking us on a journey into the unconscious brain, the two scientists who made this incredible discovery tell the amazing story of their work, and the surprising conclusion they were forced to reach. Written to be accessible to students and popular science readers, this book is a fascinating illustration of the power of the 'unconscious' mind. (shrink)

What is the nature of consciousness? How is consciousness related to brain processes? This volume collects thirteen new papers on these topics: twelve by leading and respected philosophers and one by a leading color-vision scientist. All focus on consciousness in the "phenomenal" sense: on what it's like to have an experience. Consciousness has long been regarded as the biggest stumbling block for physicalism, the view that the mind is physical. The controversy has gained focus over the last few decades, and (...) phenomenal knowledge and phenomenal concepts--knowledge of consciousness and the associated concepts--have come to play increasingly prominent roles in this debate. Consider Frank Jackson's famous case of Mary, the super-scientist who learns all the physical information while confined in a black-and-white room. According to Jackson, if physicalism is true, then Mary's physical knowledge should allow her to deduce what it's like to see in color. Yet it seems intuitively clear that she learns something when she leaves the room. But then how can consciousness be physical? Arguably, whether this sort of reasoning is sound depends on how phenomenal concepts and phenomenal knowledge are construed. For example, some argue that the Mary case reveals something about phenomenal concepts but has no implications for the nature of consciousness itself. Are responses along these lines adequate? Or does the problem arise again at the level of phenomenal concepts? The papers in this volume engage with the latest developments in this debate. The authors' perspectives range widely. For example, Daniel Dennett argues that anti-physicalist arguments such as the knowledge argument are simply confused; David Papineau grants that such arguments at least reveal important features of phenomenal concepts; and David Chalmers defends the anti-physicalist arguments, arguing that the "phenomenal concept strategy" cannot succeed. (shrink)

It is often claimed that Russellian monism carries a commitment to a structuralist conception of physics, on which physics describes the world only in terms of its spatiotemporal structure and dynamics. We argue that this claim is mistaken. On Russellian monism, there is more to consciousness, and to the rest of concrete reality, than spatiotemporal structure and dynamics. But the latter claim supports only a conditional claim about physics: _if_ structuralism about physics is true, then there is more to consciousness (...) and to the rest of concrete reality than physics describes. Given the fundamental nature of their position, Russellian monists can, we argue, deny the antecedent without inconsistency. We also draw out two significant consequences of that result. One is that it provides a response to some recent objections to Russellian monism, by Alyssa Ney and Eric Hiddleston. The other consequence concerns a line of reasoning known as _the structure and dynamics argument_—reasoning that is thought to motivate Russellian monism. In David J. Chalmers’s version, which is regarded as canonical, structuralism about physics is implied by a premise. If our main thesis is true, then that version is problematic, at least from the perspective of Russellian monists who take the argument to motivate their theory. However, we argue, the argument can be reformulated without relying on structuralism about physics. (shrink)

: Phenomenal knowledge usually comes from experience. But it need not. For example, one could know what it’s like to see red without seeing red—indeed, without having any color experiences. Daniel Dennett (2007) and Pete Mandik (forthcoming) argue that this and related considerations undermine the knowledge argument against physicalism. If they are right, then this is not only a problem for anti‐physicalists. Their argument threatens to undermine any version of phenomenal realism— the view that there are phenomenal properties, or qualia, (...) that are not conceptually reducible to physical or functional properties. I will argue that this threat is illusory. Explaining why will clarify what is and is not at issue in discussions of the knowledge argument and phenomenal realism. This will strengthen the case for physically and functionally irreducible qualia. 2 Phenomenal knowledge usually comes from experience. For example, I know what it’s like to see red because I have done so. Does knowing what it’s like to have an experience with phenomenal character X require having an experience with X? No. A famous counterexample is Hume’s missing shade of blue, in which one can extrapolate from phenomenally similar experiences (A Treatise of Human Nature, Bk. I, Pt. I, Sec. I).1 One might think that a weaker version of the no‐phenomenal‐knowledge‐without‐experience thesis remains tenable, e.g., that knowing what it’s like to see in color requires having or having had color experiences. But this thesis also seems doubtful. Peter Unger (1966) devised plausible counterexamples over four decades ago, and since then others (e.g., Lewis 1988, Alter 1998, Stoljar 2005) have done the same. One could have phenomenal knowledge of color experiences without having such experiences. Indeed, one could have such knowledge without having experiences that are remotely like color experiences. What is the significance of this observation for contemporary debates about consciousness and physicalism? Daniel Dennett (2007) and Pete Mandik (forthcoming) suggest that it undermines the knowledge argument against physicalism.2 That is because they take the claim that someone who has never seen in color could not know what it’s like to see in color to be the basis of the knowledge argument’s main epistemic premise: the premise that (roughly put) 3 no amount of physical knowledge is sufficient for phenomenal knowledge of color experiences. If they are right, then this is not only a problem for anti‐ physicalists. Many physicalists (e.g., Loar 1990/97, Papineau 2002, 2007) accept the knowledge argument’s epistemic premise. Dennett’s and Mandik’s arguments threaten all versions of what David Chalmers (2003) calls phenomenal realism, the view that there are phenomenal properties, or qualia, that are not conceptually reducible to physical or functional properties.3 I will argue that this threat is illusory. Explaining why will clarify what is and is not at issue in discussions of the knowledge argument and phenomenal realism. The net result will be to strengthen the case for physically inexplicable qualia. (shrink)

The concept that alterated communications between the gut microbiome and the brain may play an important role in human brain disorders has recently received considerable attention. This is the result of provocative preclinical and some clinical evidence supporting early hypotheses about such communication in health and disease. Gastrointestinal symptoms are a common comorbidity in patients with autism spectrum disorders (ASD), even though the underlying mechanisms are largely unknown. In addition, alteration in the composition and metabolic products of the gut microbiome (...) has long been implicated as a possible causative mechanism contributing to ASD pathophysiology, and this hypothesis has been supported by several recently published evidence from rodent models of autism induced by prenatal insults to the mother. Recent evidence in one such model involving maternal infection, that is characterized by alterations in behavior, gut physiology, microbial composition, and related metabolite profile, suggests a possible benefit of probiotic treatment on several of the observed abnormal behaviors. (shrink)

This paper replies to a number of objections brought against the solution to Jennifer Saul's puzzle of failure of substitutivity in transparent contexts presented in my 2001 paper "Alter Egos and Their Names".

Zombies make trouble for physicalism. Intuitively, they seem conceivable, and many take this to support their metaphysical possibility – a result that, most agree, would refute physicalism. John Hawthorne (2002) [Philosophical Studies 109, 17–52] and David Braddon-Mitchell (2003) [The Journal of Philosophy 100, 111–135] have developed a novel response to this argument: phenomenal concepts have a conditional structure – they refer to non-physical states if such states exist and otherwise to physical states – and this explains the zombie intuition. (...) I argue that this strategy fails. The considerations Hawthorne and Braddon-Mitchell adduce in support of their analysis in fact do no such thing. Further, their main argument for the analysis is self-defeating: exactly similar reasoning would undermine the view it is meant to establish. Finally, on closer inspection the conditional analysis is incompatible with the zombie intuition. Thus, not only is the analysis incapable of explaining the intuition: the intuition’s plausibility indicates that the analysis is incorrect. I also suggest that the allure of the conditional-analysis strategy may derive from a questionable view about what explaining the intuition would require. (shrink)

Zombies make trouble for physicalism. Intuitively, they seem conceivable, and many take this to support their metaphysical possibility – a result that, most agree, would refute physicalism. John Hawthorne (2002) [Philosophical Studies 109, 17–52] and David Braddon-Mitchell (2003) [The Journal of Philosophy 100, 111–135] have developed a novel response to this argument: phenomenal concepts have a conditional structure – they refer to non-physical states if such states exist and otherwise to physical states – and this explains the zombie intuition. (...) I argue that this strategy fails. The considerations Hawthorne and Braddon-Mitchell adduce in support of their analysis in fact do no such thing. Further, their main argument for the analysis is self-defeating: exactly similar reasoning would undermine the view it is meant to establish. Finally, on closer inspection the conditional analysis is incompatible with the zombie intuition. Thus, not only is the analysis incapable of explaining the intuition: the intuition’s plausibility indicates that the analysis is incorrect. I also suggest that the allure of the conditional-analysis strategy may derive from a questionable view about what explaining the intuition would require. (shrink)

Ideal for courses in consciousness and the philosophy of mind, Consciousness and The Mind-Body Problem: A Reader presents thirty-three classic and contemporary readings, organized into five sections that cover the major issues in this debate: the challenge for physicalism, physicalist responses, alternative responses, the significance of ignorance, and mental causation. Edited by Torin Alter and Robert J. Howell, the volume features work from such leading figures as Karen Bennett, Ned Block, David J. Chalmers, Frank Jackson, Colin McGinn, (...) class='Hi'>David Papineau, and many others. (shrink)

heories of embodied cognition (e.g., Perceptual Symbol Systems Theory; Barsalou, 1999, 2009) suggest that modality specific simulations underlie the representation of concepts. Supporting evidence comes from modality switch costs: participants are slower to verify a property in one modality (e.g., auditory, BLENDER-loud) after verifying a property in a different modality (e.g., gustatory, CRANBERRIES-tart) compared to the same modality (e.g., LEAVES-rustling, Pecher et al., 2003). Similarly, modality switching costs lead to a modulation of the N400 effect in event-related potentials (ERPs; Collins (...) et al., 2011; Hald et al., 2011). This effect of modality switching has also been shown to interact with the veracity of the sentence (Hald et al., 2011). The current ERP study further explores the role of modality match/mismatch on the processing of veracity as well as negation (sentences containing “not”). Our results indicate a modulation in the ERP based on modality and veracity, plus an interaction. The evidence supports the idea that modality specific simula- tions occur during language processing, and furthermore suggest that these simulations alter the processing of negation. (shrink)

Consider the conscious states of a single subject at a time. Arguably, split-brain cases show that such states need not be jointly accessible. It is less clear that these cases also show that such states need not be jointly experienced. Michael Tye (2004) argues split-brain cases do have that implication, and Timothy Bayne and David Chalmers (2003) argue that they do not. I will develop two objections to Tye’s arguments. First, an analogy to blindsight on which he relies is (...) questionable. Second, even if his analogy succeeds, it shows only that a single person can simultaneously have two separate sets of phenomenally conscious mental states. That result fails to undermine the phenomenalunity thesis that Bayne and Chalmers defend, on which phenomenal consciousness is necessarily unified. (shrink)

This article discusses ethical implications for the academy in the use of cyberspace and virtual reality in conducting its teaching and research responsibilities. It identifies important cyberspace ethics concerns as they intersect with the academy and provides an ethical framework for coming to grips with them. Topics discussed here include the sine qua non of academic collegiality and civility, concerns about digital alteration of images and sounds, and issues pertaining to academic administration and infrastructure.

This essay responds to the machine question in the affirmative, arguing that artifacts, like robots, AI, and other autonomous systems, can no longer be legitimately excluded from moral consideration. The demonstration of this thesis proceeds in four parts or movements. The first and second parts approach the subject by investigating the two constitutive components of the ethical relationship—moral agency and patiency. In the process, they each demonstrate failure. This occurs not because the machine is somehow unable to achieve what is (...) considered necessary and sufficient to be a moral agent or patient but because the characterization of agency and patiency already fail to accommodate others. The third and fourth parts respond to this problem by considering two recent alternatives—the all-encompassing ontocentric approach of Luciano Floridi’s information ethics and Emmanuel Levinas’s eccentric ethics of otherness. Both alternatives, despite considerable promise to reconfigure the scope of moral thinking by addressing previously excluded others, like the machine, also fail but for other reasons. Consequently, the essay concludes not by accommodating the alterity of the machine to the requirements of moral philosophy but by questioning the systemic limitations of moral reasoning, requiring not just an extension of rights to machines, but a thorough examination of the way moral standing has been configured in the first place. (shrink)

English summary: Since Herodotus and Thucydides the assumption that the historic structures of the past sooner or later reappear in the present and future has provided a methodological basis for all serious historic philosophical debate, and the ultimate social self-justification within historical disciplines. In addition to a broad methodological introduction to the subject, this volume contains selected contributions to the cyclical and biological patterns of thought in the philosophy of history including such diverse thinkers as Plato, Aristotle, Polybius, Sallust, Virgil, (...) Livy, Seneca, Orosius, Simplicius, Proclus, Joachim of Fiore, Machiavelli, Vico, Kant, Hegel, Spengler, Thomas Mann, Toynbee, Huntington and Fukuyama. German description: Seit Herodot und Thukydides gilt die Annahme, daa die historischen Strukturen der Vergangenheit fruher oder spater auch in Gegenwart und Zukunft wiederkehren, als methodologische Grundlage allen echten geschichtsphilosophischen Argumentierens und als ultimative gesellschaftliche Selbstbegrundung der historischen Disziplinen. Unter den verschiedenen diesbezuglichen Denkschulen, welche sich in der Antike und im Abenland herausgebildet haben, war die Vermutung, politische oder kulturelle Einheiten konnten sich analog zum Lebenszyklus naturlicher Korper verhalten und biologistische bzw. zyklische Etappen wie Geburt, Wachstum, Reife, Alter und Tod bzw. Neubeginn erleben, ganz besonders wirkmachtig und pragt auch heute noch unter dem Schlagwort vom Aufstieg und Niedergang der groaen Hochkulturen unser Verstandnis von den notwendigen Etappen einer jeden Zivilisation. Vorliegender Band beinhaltet, neben einer breiten methodologischen Einfuhrung in das Thema, ausgewahlte Beitrage zu zyklischen und biologistischen Denkstrukturen in der Geschichtsphilosophie so unterschiedlicher Denker wie Platon, Aristoteles, Polybios, Sallust, Vergil, Livius, Seneca, Orosius, Simplikios, Proklos, Joachim von Fiore, Machiavelli, Vico, Kant, Hegel, Spengler, Thomas Mann, Toynbee, Huntington und Fukuyama. (shrink)

Neural substrates of fatigue in traumatic brain injury are not well understood despite the considerable burden of fatigue on return to productivity. Fatigue is associated with diminishing performance under conditions of high cognitive demand, sense of effort, or need for motivation, all of which are associated with cognitive control brain network integrity. We hypothesize that the pathophysiology of TBI results in damage to diffuse cognitive control networks, disrupting coordination of moment-to-moment monitoring, prediction, and regulation of behavior. We investigate the cingulo-opercular (...) and frontoparietal networks, which are engaged to sustain attention for task and maintain performance. A total of 61 individuals with mild TBI and 42 orthopedic control subjects participated in functional MRI during performance of a constant effort task requiring altering the amount of effort utilized to manually squeeze a pneumostatic bulb across six 30-s trials. Network-based statistics assessed within-network organization and fluctuation with task manipulations by group. Results demonstrate small group differences in network organization, but considerable group differences in the evolution of task-related modulation of connectivity. The mild TBI group demonstrated elevated CO connectivity throughout the task with little variation in effort level or time on task, while CO connectivity diminished over time in controls. Several interregional CO connections were predictive of fatigue in the TBI group. In contrast, FP connectivity fluctuated with task manipulations and predicted fatigue in the controls, but connectivity fluctuations were delayed in the mild traumatic brain injury group and did not relate to fatigue. Thus, the mTBI group’s hyper-connectivity of the CO irrespective of task demands, along with hypo-connectivity and delayed peak connectivity of the FP, may allow for attainment of task goals, but also contributes to fatigue. Findings are discussed in relation to performance monitoring of prediction error that relies on internal cues from sensorimotor feedback during task performance. Delay or inability to detect and respond to prediction errors in TBI, particularly evident in bilateral insula-temporal CO connectivity, corresponds to day-to-day fatigue and fatigue during task performance. (shrink)

P.J. McGrath has recently challenged the standard claim that to escape the problem of evil one need only alter one’s conception of God by limiting his power or his goodness. If we assume that God is infinitely good but not omnipotent, then God can scarcely be a proper object of worship. And if we assume that if God is omnipotent but limited in goodness, he becomes a moral monster. Either way evil remains a problem for theistic belief. I argue (...) that McGrath fails to distinguish between the deductive and inductive problem of evil and between a limitation in God’s “strength” and a limitation in God’s “ability to act”, and that once these distinctions are made, his argument fails. (shrink)

P.J. McGrath has recently challenged the standard claim that to escape the problem of evil one need only alter one’s conception of God by limiting his power or his goodness. If we assume that God is infinitely good but not omnipotent, then God can scarcely be a proper object of worship. And if we assume that if God is omnipotent but limited in goodness, he becomes a moral monster. Either way evil remains a problem for theistic belief. I argue (...) that McGrath fails to distinguish between the deductive and inductive problem of evil and between a limitation in God’s “strength” and a limitation in God’s “ability to act”, and that once these distinctions are made, his argument fails. (shrink)

Addressing a challenge and opportunity that is definitive of life in the 21st century, this book provides a range of possible solutions that serve to motivate and structure future research and debate around the concept of 'the other' in communication.

I take issue with several themes in Ted Toadvine’s lively paper, “Limits of the Flesh,” suggesting that he has significantly misread many of the arguments in The Spell of the Sensuous. I first engage his contention that I disparage reflection and denigrate the written word. Then I take up the assertion that I exclude the symbolic dimension of experience from my account, and indeed that I seek to eliminate the symbolic from our interactions with others. Finally, I refute his claim (...) that my ecophenomenological stance leaves no room for resistance, contradiction, and alterity—elements that are, in fact, central to my understanding of ethics. My reply leads directly into a discussion of one of the crucial concerns of my work: the manner in which the very style of our discourse—our way of wielding words—tacitly works to either enhance, or to stifle, the solidarity between the human community and the more-than-human earth. (shrink)

Through a philosophical lens, this book explores the powerful educational capabilities of classic psychedelics.

This essay explores some conceptual and diagnostic frameworks to advance epistemic decolonization in the US philosophical profession. A central focus is the distinction between those philosophies of formerly colonized peoples that are culturally alterior or, simply, alterior and those that are analectical in the Dusselian sense of emerging from a subordinated political position. The paper begins by reflecting upon connections between coloniality, the alterior, and the analectical to frame the discussion of epistemic decolonization in the philosophy profession. It then considers (...) a knower's core theoretic reconstruction in the task of epistemic decolonization and identifies some ambiguities in reconciling alterior traditions with analectical theoretical reconstruction. The work of Charles Mills and Enrique Dussel are considered as case studies. The paper concludes with critical reflections on the institutional network of canon, curriculum, and other conceptual and credentialization structures that constitute institutional Eurocentrism. (shrink)

Using fMRI, we investigated how right temporal lobe gliomas affecting the posterior superior temporal sulcus alter neural processing observed during speech perception and production tasks. Behavioural language testing showed that three pre-operative neurosurgical patients with grade 2, grade 3 or grade 4 tumours had the same pattern of mild language impairment in the domains of object naming and written word comprehension. When matching heard words for semantic relatedness (a speech perception task), these patients showed under-activation in the tumour infiltrated (...) right superior temporal lobe compared to 61 neurotypical participants and 16 patients with tumours that preserved the right postero-superior temporal lobe, with enhanced activation within the (tumour-free) contralateral left superior temporal lobe. In contrast, when correctly naming objects (a speech production task), the patients with right postero-superior temporal lobe tumours showed higher activation than both control groups in the same right postero-superior temporal lobe region that was under-activated during auditory semantic matching. The task dependent pattern of under-activation during the auditory speech task and over-activation during object naming was also observed in eight stroke patients with right hemisphere infarcts that affected the right postero-superior temporal lobe compared to eight stroke patients with right hemisphere infarcts that spared it. These task-specific and site-specific cross-pathology effects highlight the importance of the right temporal lobe for language processing and motivate further study of how right temporal lobe tumours affect language performance and neural reorganisation. These findings may have important implications for surgical management of these patients, as knowledge of the regions showing functional reorganisation may help to avoid their inadvertent damage during neurosurgery. (shrink)

We examine two different descriptions of the behavioral functions of the hippocampal system. One emphasizes spatially organized behaviors, especially those using cognitive maps. The other emphasizes memory, particularly working memory, a short-term memory that requires iexible stimulus-response associations and is highly susceptible to interference. The predictive value of the spatial and memory descriptions were evaluated by testing rats with damage to the hippocampal system in a series of experiments, independently manipulating the spatial and memory characteristics of a behavioral task. No (...) dissociations were found when the spatial characteristics of the stimuli to be remembered were changed; lesions produced a similar deficit in both spatial and nonspatial test procedures, indicating that the hippocampus was similarly involved regardless of the spatial nature of the task. In contrast, a marked dissociation was found when the memory requirements were altered. Rats with lesions were able to perform accurately in tasks that could be solved exclusively on the basis of reference memory. They performed at chance levels and showed no signs of recovery even with extensive postoperative training in tasks that required working memory. In one experiment all the characteristics of the reference memory and working memory procedures were identical except the type of memory required. Consequently, the behavioral dissociation cannot be explained by differences in attention, motivation, response inhibition, or the type of stimuli to be remembered. As a result of these experiments we propose that the hippocampus is selectively involved in behaviors that require working memory, irrespective of the type of material that is to be processed by that memory. (shrink)

I take issue with several themes in Ted Toadvine’s lively paper, “Limits of the Flesh,” suggesting that he has significantly misread many of the arguments in The Spell of the Sensuous. I first engage his contention that I disparage reflection and denigrate the written word. Then I take up the assertion that I exclude the symbolic dimension of experience from my account, and indeed that I seek to eliminate the symbolic from our interactions with others. Finally, I refute his claim (...) that my ecophenomenological stance leaves no room for resistance, contradiction, and alterity—elements that are, in fact, central to my understanding of ethics. My reply leads directly into a discussion of one of the crucial concerns of my work: the manner in which the very style of our discourse—our way of wielding words—tacitly works to either enhance, or to stifle, the solidarity between the human community and the more-than-human earth. (shrink)

Is writing a world art history possible? Does the history of art as such even exist outside the Western tradition? Is it possible to consider the history of art in a way that is not fundamentally Eurocentric? In this highly readable and provocative book, David Carrier, a philosopher and art historian, does not attempt to write a world art history himself. Rather, he asks the question of how an art history of all cultures could be written—or whether it is (...) even possible to do so. He also engages the political and moral issues raised by the idea of a multicultural art history. Focusing on a consideration of intersecting artistic traditions, Carrier negotiates the way meaning and understanding shift or are altered when a visual object from one culture, for example, is inserted into the visual tradition of another culture. _A World Art History and Its Objects _proposes the use of temporal narrative as a way to begin to understand a multicultural art history. ��. (shrink)

Is writing a world art history possible? Does the history of art as such even exist outside the Western tradition? Is it possible to consider the history of art in a way that is not fundamentally Eurocentric? In this highly readable and provocative book, David Carrier, a philosopher and art historian, does not attempt to write a world art history himself. Rather, he asks the question of how an art history of all cultures could be written—or whether it is (...) even possible to do so. He also engages the political and moral issues raised by the idea of a multicultural art history. Focusing on a consideration of intersecting artistic traditions, Carrier negotiates the way meaning and understanding shift or are altered when a visual object from one culture, for example, is inserted into the visual tradition of another culture. _A World Art History and Its Objects _proposes the use of temporal narrative as a way to begin to understand a multicultural art history. ��. (shrink)

The ambivalence of human-animal-relationships culminates in our eating habits; most people disapprove of factory farming, but most animal products that are consumed come from factory farming. While psychology and sociology offer several theoretical explanations for this phenomenon our study presents an experimental approach: an attempt to challenge people’s attitude by confronting them with the animals’ perspective of the consumption process. We confronted our participants with a fictional scenario that could result in them being turned into an animal. In the scenario, (...) a wicked fairy forces them to choose a ticket. Depending on their choice of ticket they have equal chances of becoming a human being with a certain consumption behaviour (meat eater, organic eater, vegetarian, vegan) or, correspondingly, becoming a certain kind of animal (factory farmed meat animal, organically farmed meat animal, animal for dairy/egg production, free living animal). Our results indicate a strong discrepancy between people’s actual consumption habits (mostly regular meat eaters) and their choices in the experiment (strong preferences for the organic or vegan life style). The data reveal a broad spectrum of explanations for people’s decisions in the experiment. We investigated the influence of four different factors on the participant’s choices in addition to reasons they gave as open-ended answers. Correspondingly, different coping strategies to overcome the tension (cognitive dissonance) between real-life consumption choices and attitudes towards nonhuman animals could be detected. Furthermore, many participants indicated a lack of knowledge concerning living conditions in farming but also concerning capacities and properties of nonhuman animals. (shrink)